June 15th, Kinjun Data, Japan's Kyoto University iPS Cell Research Institute recently issued a statement, stating that the phase II clinical trial of bosutinib for amyotrophic lateral sclerosis (ALS) patients, also known as 'Lou Gehrig's disease', showed that this chronic myeloid leukemia treatment drug can effectively control the progression of ALS symptoms. The phase II clinical trial started in 2022, with 26 ALS patients receiving continuous treatment for 24 weeks. The trial results showed that more than half of the patients had their symptoms controlled and did not experience the specific adverse events of ALS. However, some patients experienced adverse reactions such as diarrhea and liver dysfunction. The researchers believe that it may be necessary to adjust the usage and dosage of bosutinib and provide some supportive therapy.

On June 4th, Jinshi Data reported that the production and sales of electric medium and heavy-duty trucks increased by 77.60% and 70.67% respectively from January to May this year. The production and sales of methanol hydrogen power systems increased by 113.38% and 92.75% respectively, and both major business zones achieved high-speed growth.

Odaily Planet Daily News Chain Game Cellula has updated its charging, refund policies, and details of the upcoming Token Generation Event (TGE). Cellula states that charging helps the sustainable development of the project, ensures fair competition for new players, and avoids turning the "Game of Life" into a social media traffic game rather than a true GameFi experience. Early supporters will receive an additional 1 million CELL tokens as a token of appreciation, but no more refunds will be provided for charges in the future. CELL tokens will be available for collection on May 28th at 13:00 (UTC). The TGE is scheduled to be held in the third quarter of 2024, but no later than the fourth quarter. (Medium)

On May 22nd, Jin10 Data reported that the Pudong New Area Biomedical Industry Innovation and Development Conference was held at the Pudong New Area Office Center. It was learned at the conference that this year, Pudong New Area in Shanghai has approved the marketing of 3 innovative drugs, and there are 16 new drugs in the application phase for marketing. Up to now, there have been 24 domestic innovative drugs approved for marketing in Pudong New Area. The conference also released the 2024 achievements of biomedical innovation in Pudong New Area, including Kaixing Life's CAR-T cell therapy Zekoviola Injection (Sai Kaize®), Kechow Pharmaceutical's first domestically produced MEK inhibitor Trametinib Capsules (Ke Luping®), Beida Pharmaceutical's third-generation EGFR inhibitor Rizotinib Hydrochloride Capsules (Rui Bida®), etc.

On May 9, Jimin Medical issued an announcement on the risk warning of stock trading, and the current stem cell drug research and development pipeline of Boao International Hospital mainly includes adipose mesenchymal stem cells (ADSC) for retinitis pigmentosa (RP), adipose mesenchymal stem cells (ADSC) for type 2 diabetes mellitus (T2DM), and adipose mesenchymal stem cells (ADSC) for chronic obstructive pulmonary disease (COPD), but they are all in the preclinical stage and the project is relatively early. The R&D cycle of innovative drugs is long, the links are long, and the risk is high, and it is easy to be affected by long factors such as technology, approval, and policy from development, clinical trials, approval to production, and there are long uncertainties in the subsequent R&D promotion.

Longpan Technology stated on May 6th on the interactive platform that the company currently does not have any products applied in the field of low-altitude aircraft and drones in terms of the hydrogen fuel cell industry chain, but the company's IV type hydrogen storage cylinder has been used in this field.

Two independent research teams have successfully regenerated brain circuits in mice using neurons grown from rat stem cells. These two studies were published on April 25th in the journal "Cell," providing valuable insights into how brain tissue forms and offering new approaches to restoring brain function lost due to disease and aging.

The United Nations Assistance Mission for Iraq (UNAMI) issued a statement in English, Arabic, and Kurdish on April 27, local time, condemning the attack on the Khor Mor gas field in Sulaymaniyah Province, Kurdistan Region of Iraq. UNAMI mourns the victims of the attack, expresses sincere condolences to the injured and the families of the victims, and calls for an investigation into the attack to determine the identity of the attackers and bring them to justice. According to a statement by the Security Media Cell, affiliated with the Iraqi Joint Operations Command, the Iraqi government has formed a technical investigation team to investigate the attack on the Khor Mor gas field.

On April 26, Aiko announced that its subsidiary, Zhejiang Aiko Solar Energy Technology Co., Ltd., plans to sign the "Equipment Procurement Contract" with Zhuhai Max Automation System Co., Ltd. to purchase a total of 74 sets of TOPCon cell wet production equipment, with a total contract amount of 214 million yuan (tax included), constituting a related party transaction.

According to official news, Klaytn recently announced that DWF Labs became a member of the Klaytn Governance Committee (GC), and its GC membership application (KGP-28) passed the on-chain vote with 98% of the votes in favor. DWF Labs will independently purchase the required 5 million KLAY to take on the role of Core Cell Operator (CCO). As a GC member, DWF Labs will strategically drive innovation and rise, foster dynamic synergies, and advance the Klaytn ecosystem.

According to Cipher, founder of JoyID, co-founder of CELL Studio, and researcher at Nervos Network, he is pleased to introduce the RGB++ protocol testnet implementation to developers and early adopters. Now everyone can deploy and interact with Turing-complete scripts on the Bitcoin network in a permissionless and trustless manner.

According to data from Odaily Planet Daily Nansen 2, Smart Money's 24-hour fund inflow tracking list on the Ethereum network is as follows: MATIC: about $6.278 million, now quoted at $0.9885, up 1.88% in 24H; CELL: about $2.552 million, now at $1.58, up 13.9% in 24H; WBTC: about $2.482 million, now at $64404.2, up 0.57% in 24H.

Red Cell Partners, an incubator investment institution, announced that it is funding a $3 million Pre-Seed round of funding for Eyris, which is known to provide blockchain-based security and ransomware defense products. （_utivebiz）

PANews reported on February 2 that according to Bloomberg, the U.S. Department of Justice (DOJ) said that FTX's theft of more than $400 million in assets on the day of Rekt was due to a SIM swap attack. According to the indictment filed in federal court in Washington, between March 2021 and April 2023, three suspects, Robert Powell, Carter Rohn and Emily Hernandez, collected the personal data of about 50 victims and used the information to persuade cell phone providers to transfer victims' phone numbers to their virtual phones, which in turn hacked into victims' financial accounts and crypto Wallets by intercepting text messages, including MFA codes. On November 11, 2022, Hernandez used a fake ID with FTX employee details to convince AT&T to transfer the mobile phone account to another SIM card. Powell then used multiple authentication codes to access FTX's crypto Wallet. The three have been charged with fraud and identity theft. According to previous news, FTX was attacked by Hacker on the night of the Rekt filing, and the Hacker stole more than $450 million in assets from FTX's hot wallet.

The three were indicted for orchestrating a SIM swap scam to steal more than $400 million from FTX, a Crypto Assets exchange that was in the midst of Rekt. According to an indictment filed by the Department of Justice in federal court in Washington, Robert Powell, Emily Hernandez, and Carter Rohn collected the personal data of about 50 victims and used that information to convince cell phone service providers to transfer victims' phone numbers to fake phones in their possession. Doing so allowed the trio to intercept text messages — including multi-factor authentication codes, which allowed them to break into victims' financial accounts and crypto Wallets. The indictment does not mention FTX, but two people familiar with the case confirmed that the "victim company-1" in the court documents was actually FTX. On or about November 11, 2022, Hernandez used a fake ID with FTX employee details to convince AT&T to transfer the mobile phone account to another SIM card. The gang's alleged mastermind, Powell — using the nicknames 'R$' and ElSwapo1 online — then used various authentication codes to access FTX's crypto Wallet.

Recently, the 37th Annual Conference on Neural Information Processing Systems was held in New Orleans, USA, as reported by IT House on December 31. At the meeting, a scientific team proposed that the artificial intelligence model Transformer has a function similar to the NMDA receptor. In addition to this discovery, they also designed new nonlinear functions that allow the Transformer model to simulate the kinetic performance of NMDA receptors. The NMDA receptor is a "smart" channel that promotes the formation of memories and skills. If glutamate is present in the brain, nerve cells become excited, delivering neurotransmitters to NMDA receptors. At the same time, magnesium ions are responsible for the gatekeeping, and when magnesium ions are squeezed out of the NMDA receptors, the neurotransmitter is allowed to enter the next nerve cell. In the hippocampus, the smooth transfer of matter ensures that short-term memory is effectively converted into long-term memory, and magnesium ions are responsible for selectively allowing matter to pass through. In the new study, the scientists found that there is a process similar to the magnesium ion gatekeeping in the NMDA receptor in the Transformer model, and that adjusting the parameters of the Transformer model can enhance the memory capacity of the model. This finding prompted researchers to think about whether it is possible to develop a method to regulate the memory consolidation process of the Transformer model by studying the mechanism of magnesium ion gatekeeping in the NMDA receptor, and make the model have systematic long-term memory and even consciousness.

PANews reported on November 24 that according to the Wall Street Journal, SBF was placed in the same cell as former Honduran President Juan Orlando Hernández, who was awaiting trial for accepting bribes from drug dealers. According to lawyer Hernández, the two have a good relationship and have had a "cordial conversation". Also held in the same cell is former Mexican police chief Genaro García Luna, who was recently convicted of aiding drug cartels in smuggling cocaine into the United States. The Wall Street Journal added that SBF's requirement to eat a vegetarian diet and take ADHD medication in prison has been addressed. At the same time, SBF was allowed to meet with non-lawyer visitors once a week. He was also allowed to use a special laptop to view legal documents, though his computer could only be used in a dedicated room. SBF spokesman Mark Botnick said SBF was "doing everything it could in this situation". In addition, SBF exchanged mackerel (a common edible fish found off the western Pacific and Atlantic coasts that can be eaten, salted and canned) with other prisoners in exchange for service. Before the November trial, he traded an unknown amount of mackerel for a haircut. According to a person familiar with the matter, SBF also provided cryptocurrency investment advice to the guards. It is reported that SBF is currently being held at the Metropolitan Detention Center in Brooklyn, which is notorious for its poor conditions. He will then be transferred to federal prison to serve his sentence, where he may have access to greater freedom of movement and better educational and recreational resources. Although SBF has been convicted, it has not yet been sentenced. His sentencing will take place on March 28, 2024. SBF currently faces a maximum sentence of 115 years in prison, although some experts believe he will be sentenced to up to 25 years.

Crypto Investors Lost $685.5 Million Last Quarter, Up 59% Over 2022 According to a report by Immunefi, crypto investors lost $685.5 million in Q3 2023, a 59% increase from the previous year. Two major hacks in Mixin Network and Multichain accounted for nearly half of the stolen amount. The recovery rate for stolen funds dropped to 8.9% in Q3, with North Korean hacker cell Lazarus Group responsible for $208.6 million of the total losses

According to news on September 11, a San Francisco federal court judge ordered Ahmad Wagaafe Hared, a young hacker suspected of stealing cryptocurrency from Northern California cryptocurrency executives, to hand over nearly $5.2 million worth of Bitcoin and a sports car to the FBI. Prosecutors said Hared and his associates first obtained the personal contact information of executives and investors, contacted cell phone service providers, and manipulated company representatives into thinking they were the legitimate owners of the targeted phone numbers. Hared then transferred the target phone number to his own phone and performed a SIM swap. Hared then hacked into emails and other accounts and stole cryptocurrency. Hared signed a plea agreement in 2019.

PANews, September 9, CoinDesk reported that SBF lawyer Mark Cohen said in a memo late on Friday that prosecutors exaggerated SBF’s real access to defense materials. Cohen said that when SBF was taken to a jail cell in the Southern District of New York Court, he still had no access to the Internet and was nowhere near the level that the Justice Department said he had access to the Internet. SBF's defense team has sought to have him temporarily released or given more computer access to mount a defense, saying his Sixth Amendment rights were violated; while prosecutors insist they revoked bail last month on public safety grounds. Finally, SBF can obtain defense materials. Almost a full month has passed since SBF was remanded in custody, and time has been lost to effectively prepare for trial. Therefore, Cohen asked the court to order the temporary release of SBF.

Golden Finance reported that the defense lawyer of FTX founder SBF stated in a memo on Friday night that prosecutors are investigating the amount of defense materials obtained by FTX founder SBF. Defense attorney Mark Cohen said in a signed letter that SBF was still unable to access the Internet properly when he was taken to a cell block in the Southern District of New York Courthouse. SBF's defense team sought to have him temporarily released or given more computer access to mount a defense, saying his Sixth Amendment rights were violated. Prosecutors insisted he had access to defense materials after his bail was revoked last month on public safety grounds.

PANews, August 31, according to The Block, a New York District Court judge argued with lawyers for FTX founder Sam Bankman-Fried (SBF) at a hearing on Wednesday because SBF’s lawyers opposed the U.S. Department of Justice. Using millions of pages of documents as evidence and claiming that the internet in prisons is terrible. The problem is that the SBF's lawyers said they had received millions of pages of documents over the past weeks and days, and that the information "came too late" for the SBF to view the documents as it would have done on bail. "So we are faced with addressing the issue of producing millions of pages of documents in the four weeks leading up to trial that our own clients were unable to review." Judge Lewis Kaplan of the U.S. District Court for the Southern District of New York said there was no evidence that the government did not act in good faith. The August document was only recently obtained from Google due to a "log file error" and the SBF knew about it long ago; more importantly, What’s surprising is that the vast majority of these documents came from the defendants’ own Google accounts. Judge Kaplan gave SBF's attorneys until Friday to submit a request to postpone the Oct. 3 trial, but said he would not necessarily grant it. Lawyers for SBF also argued that the laptop SBF received had a short battery life, there were no power sockets in the cell to charge it, and the internet was poor during half of the sessions, so it was hoped that SBF would be released temporarily before trial. Judge Kaplan asked why an extension cord couldn't be used, but prosecutors said it posed a safety risk. The judges hope to submit a joint report on prison conditions by Tuesday morning.

According to a court filing on Tuesday, federal prosecutors are rebutting former FTX CEO SBF's claim that his use of a special laptop and other court-ordered conveniences during his imprisonment did little to help him prepare his defense, Jinse Finance reported. Lawyers for SBF asked the U.S. District Court for the Southern District of New York to provide their client with a laptop with Internet access and access to his jail cell at the federal courthouse in Manhattan, New York, five days a week in the weeks leading up to the October trial. However, prosecutors argued that the technical restrictions imposed on SBF were merely an "inconvenience" that did not impede his defense preparation and were necessary due to what he called "witness tampering." SBF lost his chance to bail earlier this month after Judge Kaplan ruled that SBF attempted to intimidate former company executives, including former Alameda Research co-CEO Caroline Ellison, in order to circumvent bail restrictions.

Artificial intelligence (AI)-powered eye scans can detect Parkinson's disease before people show symptoms, a study suggests. It is reported that using AI to analyze ocular OCT scan data can detect differences in the thickness of the eye cell layer between patients with Parkinson's disease and non-patients. This may detect the disease up to 7 years before symptoms appear. Researchers believe eye scans can detect the disease earlier and hope to make them routine in the future. OCT scans are already widely used in ophthalmology due to their non-invasive nature and are expected to be extended to the NHS.

Artificial intelligence (AI)-powered eye scans can detect Parkinson's disease before people show symptoms, a study suggests. It is reported that using AI to analyze ocular OCT scan data can detect differences in the thickness of the eye cell layer between patients with Parkinson's disease and non-patients. This may detect the disease up to 7 years before symptoms appear. Researchers believe eye scans can detect the disease earlier and hope to make them routine in the future. OCT scans are already widely used in ophthalmology due to their non-invasive nature and are expected to be extended to the NHS.

According to the "Kechuangban Daily" report on August 3, scientists at the University of Pennsylvania in the United States used artificial intelligence to analyze the protein data of modern humans and human extinct relatives Neanderthals and Denisovans, and identified the latter two. Molecules made by humans that kill disease-causing bacteria and synthesized. The latest research is expected to help scientists develop new types of drugs. Relevant papers were published in the latest issue of the journal Cell Host and Microbe. Many organisms, including humans, produce peptides with antimicrobial properties, and peptides produced by extinct human relatives such as Neanderthals and Denisovans may be useful to modern bacteria, the team noted.